Brownian dynamics simulations of ionic current through an open channel
نویسندگان
چکیده
Ionic motion through an open ion channel is analyzed within the framework of selfconsistent Brownian dynamics. A novel conceptual model in which the ions motion is coupled to the vibrations of the pore walls is introduced. The model allows to include into simulations an important additional mechanism of energy dissipation and the effects of self-induced strong modulation of the channel conductivity.
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تاریخ انتشار 2005